Shoolini University of Biotechnology and Management Sciences is a research-driven private university. The main focus of the University is on innovation, quality placements, and world-class faculty. Read on to know the ongoing happenings and research breakthroughs done by Shoolini!
Blood pressure regulator from bark of pine trees
Date: June 19, 2019
Despite strenuous efforts by various health organisations, hypertension continues to be one of the leading lifestyle diseases of the present times. This disease can further cause kidney dysfunction, heart disease, stroke, and other health complications.
Researchers at School of Biotechnology have screened pycnogenol, a polyphenolic compound extracted from Pine tree as a promising blood pressure regulator. In their attempts to find out the pathway and the mechanism of the Bio-active compound present in the medicinal plants used for their anti-hypertensive properties in traditional medicines. Various synthetic drugs such as telmisartan, candesartan, and olmesartan are targeted for the AT1 receptor for controlling systolic blood pressure by blocking its effect.
“Pycnogenol also acts as ARBs (angiotensin-receptor blockers) as it is also targeted for the Angiotensin Type-1 (AT1R) receptor in the renin-angiotensin system, that regulates Blood Pressure. Angiotensin -1 receptor is a peptide hormone that causes vasoconstriction and an increase in blood pressure”, stated Dr. Azhar Khan.
Though natural compounds have significantly lesser side-effects because of their lower yield, synthetic drugs are usually preferred over them for alternate therapy. Thus, the discovery of new natural compounds and study of their medicinal properties can be a huge advantage.
Further, Pine trees are readily available in the lower Himalayan region giving the local people another regional advantage from the economic perspective. The patent titled Polyphenolic compound pycnogenol from Pinus Pinaster Target angiotensin type 1 receptor a promising blood pressure regulator; has been co-filed by Dr. Azhar Khan, Huma Khan, Nitika Chauhan, and Dr. Saurabh Kulshrestha. Dr. Khan’s Lab is involved in exploring and screening of various plants for their antihypertensive properties and found better results in the plant extract obtained from the bark of Pine tree. Huma Khan is a Ph.D. scholar and is working on the natural compounds derived from medicinal plants for the targets of anti-hypertension. Mr. Varun Jaiswal, Assistant Professor, School of Electrical and Computer Science Engineering is involved in docking studies.
Prof. Saurabh Kulshreshtha is involved in the screening of the medicinal plants from the Himalayan region. Nitika Chauhan is currently pursuing her post-graduation from Shoolini and was involved in generating the library of bio-active compounds.
Making hydropower more cost efficient
Date: June 19, 2019
Energy is an essential component for under-developed countries for financial improvement and social progression leading to human welfare. With a specific end goal to take care of the demand for electricity, hydro-based projects are one of the most cost-effective means for power generation. Hydropower is one of the significant sources of electricity in the region, and the erosion of hydro turbine fragments is a vital issue for the capable operation of hydropower plants.
During monsoon, the silt gets mixed with the flowing water which clashes with the blades of a hydropower plant leading to the steady removal of material from the surface of the Pelton blades reducing the power output and efficiency of the power plants.
The School of Mechanical and Civil Engineering at Shoolini University has designed a silt erosion test apparatus to make the performance analysis of a hydropower plant. Blades have to be changed every 2-3 years, and it is tough to observe this entire phenomenon on a large scale directly. The innovation can reduce the observation period from 2-3 years to 2-3 months and can also help in placing barriers at a more appropriate level based on the observations over time to reduce the erosion level.
The mechanism of erosion is complicated because of the connection of a few elements viz. size of particles, shape, hardness, concentration, speed, impingement point, and properties of the material. The performance analysis was done based on various parameters, for example, silt size, jet velocity, silt concentration, and operating hours. The researchers observed from this small scale apparatus that with an increase in silt size, jet velocity, silt concentration and working hours the performance of Pelton runner in terms of power output and efficiency of the power plant is going to decline.
The created relationships can prove to be helpful for turbine producing enterprises keeping in mind the end goal to foresee the quantum of erosion in Pelton turbine pail at the assembling stage.
This design patent entitled “Silt erosion test apparatus for the turbine,” filed by Dr. Robin Thakur was granted in May this year. Dr. Thakur is an Assistant Professor in the School of Mechanical and Civil engineering and thanked his guide, Dr. Anil Kumar, for his invaluable contributions to the research work. Another patent filed by Dr. Thakur along with Dr. Kumar, Mr. Nitin Rana, and Mr. Amar Raj Singh is a semi-rotary compressor with a compact and better air-cooled design for better efficiency, cooling, and lubrication. It was granted this year on June 6.
Patent for cost-effective solar tracking panels
Date: June 19, 2019
Energy and power have become an essential requirement of the modern era. As concerns for depleting fuels and non-renewable sources of energy are growing, harnessing solar power is being recognized as a potential solution for minimizing our dependency on fuels like coal and petroleum.
"There are rural areas in India even now where residents do not have a proper electricity supply, because it is not economical for the government to supply the electricity in certain areas because of their geological location or some other reason," stated Mr. Sorabh Aggarwal, an Assistant Professor, School of Mechanical and Civil Engineering.
He added that to solve this issue, a small rooftop solar system could be a good option, but the problem of using solar panels is that they are stationary whereas the sun is always changing its direction. Hence solar radiations do not directly reflect on the panel, which reduces its efficiency.
Though, many sun tracking systems are available in the market; they are too costly to be used at a small scale. Shoolini Faculty members have come up with a cost-effective sun tracking system for individuals or small users which can always keep the panel in the direction of the sun for maximizing the utility of solar panels. The design patent filed last year by the Shoolini Professors on the proposed solar tracking system was granted earlier on August 24 in 2018, this year. The patent has been submitted by Mr. Sorabh Aggarwal, Assistant Professor, Dr. Neeraj Gandotra, Associate Professor, School of Mechanical and Civil Engineering and Prof Bhaskar Goel, Head of School of Mechanical and Civil Engineering.
Mr. Aggarwal said that the team is still working on the various other aspects of the project and also thanked Vice Chancellor Prof PK Khosla for his support. He added, "Our Vice-Chancellor is always open to many research ideas and his enthusiastic support at all times has created a positive atmosphere for the researchers.”
Yogic techniques for thyroid patients
Date: June 19, 2019
The thyroid is a chronic disease and is becoming increasingly common in modern times. The potency of the medications continue to increase with time for a patient but has no long-term effects, nor there is a permanent cure for the disease. The thyroid is a small gland in the neck that makes thyroid hormones. These hormones are necessary for all the cells in the body to work normally. Sometimes the thyroid produces too much or too little of these hormones. Too much thyroid hormone is called hyperthyroidism and can cause many of your body's functions to speed up. Thyroid disorders are very common and tend mainly to occur in women, although men, teenagers, children, and babies, too can be affected. Data shows that one in 20 persons has some thyroid disorder, which may be temporary or permanent.
A patent entitled 'specific yoga protocol effective for hypothyroidism patients' has been filed by Dr. Subodh Saurabh Singh and Dr. Mala Tripathi of Shooloni University last month. The 23-minute yoga protocol includes four asanas, namely Ustrasana, Marjariasana, Singhgarjanasana, Suptavarjasna (or Matasayaasana) and Sarvangasana and one pranayama, Ujayi Pranayama.
Dr. Subodh said, "This yoga protocol has shown positive results in patients with thyroid levels below the threshold. They are suggested to start yoga exercises along with their prescribed medications, and in many cases, patients are also able to regulate the thyroid levels with the decreased dosage of their medicines over time."
He added that though the yoga practices are known to have long term effects, it is strongly recommended to continue the yogic exercises even after the initial results as the effects start diluting after an individual stops the regular practice. He said Yoga is “very effective but is very sensitive too. So, people should practice yoga in the presence and guidance of a good yoga expert to avoid reverse side effects. Yoga is the only discipline that fulfills all six dimensions of well-being. It is known to prevent diseases and promotes mental and social well-being as well.”
Dr. Subodh and Dr. Mala Tripathi have completed their master's in Yogic Science and Holistic Health from Dev Sanskriti University, Haridwar and Ph.D. from Mahatma Gandhi Chitrakoot University, Satna. They have worked in Morarji Desai National Institution of Yoga, New Delhi for eight and six years respectively and joined Shoolini University as Assistant Professors in the School of Yoga and Naturopathy in May 2018.