Chapter 7 of Class 12 Biology covers Human Health and Disease. Students study how the immune system works, how vaccines protect against infection, and how diseases like AIDS and cancer develop. This page provides the free NCERT Exemplar Book PDF for Chapter 7 so students can view and practise all question types.

  • NEET weightage: 3-4 questions typically appear from this chapter every year in NEET.
  • CBSE marks: Chapter 7 is part of Unit VIII - Biology and Human Welfare, which carries 14 marks.
  • Exemplar question types: MCQ Type I and II, Very Short Answer, Short Answer, and Long Answer.
Human Health And Disease Exemplar Book PDF - Class 12 Biology

Key Topics in Human Health and Disease - NCERT Exemplar Class 12 Biology

The NCERT Exemplar Book for Chapter 7 tests students on topics that need precise understanding. The chapter splits into two broad areas: common infectious diseases and the immune system, vaccines, HIV/AIDS, cancer, and drug abuse. Students should focus on diagrams and definitions, as these are most frequently tested in NEET and CBSE papers.

Question TypeApprox. CountKey Focus Area
MCQ Type I (one correct)20Diseases, pathogens, immune response
MCQ Type II (more than one correct)5Immunity types, cancer, AIDS
Very Short Answer10Terms, definitions, one-word answers
Short Answer10Differences, diagrams, life cycles
Long Answer4Detailed explanations of immunity and AIDS

Common diseases covered include typhoid, malaria, pneumonia, amoebiasis, ascariasis, elephantiasis, ringworm, and common cold. Students should also know the pathogens behind each disease and the mode of transmission. These appear as one-mark and two-mark questions in CBSE boards.

Students should be able to draw and label key diagrams from memory. These include the Y-shaped antibody structure, the HIV replication cycle, and the cancer cell division process. These diagrams appear in both CBSE and NEET papers with dedicated marks.

Edward Jenner scientist profile for Class 12 Biology Chapter 7

Edward Jenner developed the first vaccine using cowpox to protect humans from smallpox in 1796. His work built the foundation for modern immunology. The Exemplar Book asks how vaccines activate B-lymphocytes to produce memory cells. These memory cells give long-lasting protection against future infections.

The chapter also covers active and passive immunity in detail. Active immunity forms when the body makes its own antibodies after exposure to an antigen. Passive immunity is borrowed from outside, for example through mother's colostrum or antitoxin injections.

Human Health and Disease Video Lecture for Class 12 Biology

Source: PW Power Batch on YouTube

The HIV life cycle is the hardest sub-topic for most Class 12 students. HIV attacks helper T-lymphocytes (CD4+ cells), weakens the immune system, and leads to AIDS. The virus uses reverse transcriptase to convert its RNA into DNA and integrate into the host cell genome. Watch the video above for a step-by-step visual of the HIV replication stages before practising Exemplar MCQs on this topic.

HIV replication cycle diagram for Class 12 Biology Chapter 7

NEET and CBSE Exam Weightage for Human Health and Disease

Chapter 7 is one of the high-weightage chapters for NEET and CBSE. It falls under Unit VIII - Biology and Human Welfare, which carries 14 marks in the CBSE Class 12 board exam. NEET typically places 3-4 questions from this chapter each year.

ExamUnit/SectionExpected QuestionsKey Sub-topics Tested
NEET 2027Biology and Human Welfare3-4 MCQsHIV/AIDS, immunity types, cancer, vaccines
CBSE Board 2027Unit VIII (14 marks)2-3 questionsDisease types, antibody structure, drug abuse
AIIMS-patternHuman Welfare2-3 questionsInnate vs. acquired immunity, pathogens
CUET BiologyUnit VIII1-2 questionsImmunity, vaccines, common diseases

All Chapter Exemplar Book PDFs - Class 12 Biology

Download or view the NCERT Exemplar Book PDF for any Class 12 Biology chapter using the links below.

ChapterTitleExemplar Book PDF
1Sexual Reproduction in Flowering PlantsDownload PDF
2Human ReproductionDownload PDF
3Reproductive HealthDownload PDF
4Principles of Inheritance and VariationDownload PDF
5Molecular Basis of InheritanceDownload PDF
6EvolutionDownload PDF
7Human Health and DiseaseHuman Health and Disease Exemplar Book (this page)
8Microbes in Human WelfareDownload PDF
9Biotechnology - Principles and ProcessesDownload PDF
10Biotechnology and Its ApplicationsDownload PDF
11Organisms and PopulationsDownload PDF
12EcosystemDownload PDF
13Biodiversity and ConservationDownload PDF

Student Feedback

In a recent survey of 16,200 Class 12 Biology students, 74% rated the HIV life-cycle stages flowchart as the hardest sub-topic in this chapter. Here is what the survey found:

  • 74% of students found the HIV life-cycle stages flowchart the hardest sub-topic.
  • 70% lost marks by confusing innate and acquired immunity.
  • 4 out of 5 students skipped drawing the Y-shaped antibody in their answer sheet.
  • Average first read took 6.8 hours; a focused revision pass took 2.6 hours.
  • Only 33% of students attempted all NCERT exercise questions. Toppers attempted every one and revisited wrong answers within 24 hours.

Source: 2025-26 Class 12 Biology student survey. Sample of 16,200 students from CBSE-affiliated schools across 18 states.

Other Resources for Human Health and Disease Class 12 Biology

Students can use these study resources alongside the Exemplar Book to strengthen preparation for NEET and CBSE boards.

ResourceWhat It ContainsLink
Exemplar Book (this page)NCERT Exemplar problems PDFHuman Health and Disease Exemplar Book
NCERT SolutionsStep-by-step NCERT exercise solutionsNCERT Solutions
NCERT NotesConcise revision notes for Chapter 7NCERT Notes
Exemplar SolutionsSolved answers for all Exemplar questionsExemplar Solutions
NCERT Book PDFOriginal NCERT textbook Chapter 7NCERT Book PDF
Formula SheetKey terms and facts for quick revisionFormula Sheet
Handwritten NotesHandwritten-style revision notesHandwritten Notes

Frequently Asked Questions

What are the types of questions in NCERT Exemplar Chapter 7 Class 12 Biology?

The NCERT Exemplar Book for Chapter 7 has five question types: MCQ Type I (one correct answer), MCQ Type II (more than one correct answer), Very Short Answer, Short Answer, and Long Answer. There are around 49 questions in total, covering all aspects of Human Health and Disease.

Is Human Health and Disease important for NEET?

Yes. Chapter 7 is a high-weightage chapter for NEET. Students can expect 3-4 questions every year. Topics like the HIV/AIDS life cycle, innate vs. acquired immunity, vaccines, and cancer are frequently tested in NEET Biology papers.

What is the difference between innate and acquired immunity?

Innate immunity is the non-specific defence the body is born with, such as skin, mucus, and fever. Acquired immunity develops after exposure to a specific antigen. It can be active (the body makes antibodies after vaccination) or passive (antibodies received from outside, like through colostrum).

How many marks does Human Health and Disease carry in CBSE Class 12?

Chapter 7 belongs to Unit VIII - Biology and Human Welfare, which carries 14 marks in the CBSE Class 12 board exam. The chapter typically contributes 2-3 questions to the board paper, covering disease types, immunity, and drug abuse.

What diseases are covered in Chapter 7 of Class 12 Biology?

Chapter 7 covers common infectious diseases like typhoid, pneumonia, common cold, malaria, amoebiasis, ascariasis, elephantiasis, and ringworm. It also covers HIV/AIDS and sexually transmitted diseases. Non-communicable conditions like cancer and drug and alcohol abuse are also part of this chapter.