The UP Board Class 12 Biology 2026 question paper with solutions (Set 348 EL) is available here for free download. UP Board Class 12 Biology 2026 was conducted by the Uttar Pradesh Madhyamik Shiksha Parishad (UPMSP) on February 23, 2026, in the afternoon shift, as a 70-mark paper of 32 questions to be solved in 3 hours 15 minutes.

UP Board Class 12 Biology 2026 Question Paper with Solutions (Set 348 EL) Download PDF Check Solutions

UP Board Class 12 Biology 2026 (Set 348 EL) Questions with Solutions

Question 1:

Testosterone hormone is synthesized and secreted by:

  • (A) Epididymis
  • (B) Sertoli cells
  • (C) Sperm
  • (D) Leydig cells

Question 2:

The phenotypic ratio of classical Mendelian dihybrid cross is:

  • (A) 1 : 2 : 1
  • (B) 3 : 1
  • (C) 9 : 7
  • (D) 9 : 3 : 3 : 1

Question 3:

The enzyme that makes a cut at a specific position within the DNA is called:

  • (A) Exonuclease
  • (B) Endonuclease
  • (C) Ligase
  • (D) Polymerase

Question 4:

Which of the following is an attribute characteristic of a population?

  • (A) Birth rate
  • (B) Death rate
  • (C) Sex ratio
  • (D) All of the above

Question 5:

Name the type of pollination found in cleistogamous flowers. Give one example.


Question 6:

How many chromosomes are found in primary spermatocytes and secondary oocytes of a human being?


Question 7:

Write the two general laws of inheritance proposed by Mendel.


Question 8:

Name any two autosome linked recessive disorders.


Question 9:

Give an example of an ecosystem where the pyramid of biomass is inverted.


Question 10:

Name the two strands of the structural gene DNA of a transcription unit.


Question 11:

Explain two phenomena which lead to variation in DNA.


Question 12:

Name the pathogenic organisms of the following diseases: (i) Pneumonia (ii) Amoebiasis (iii) Ascariasis (iv) Filaria.


Question 13:

Why is the pyramid of energy never inverted? Explain.


Question 14:

What do you mean by detritus and detritivores?


Question 15:

With the help of a suitable diagram, describe the functions of the vegetative and generative cells of mature pollen grains.


Question 16:

Write a short note on polyembryony.


Question 17:

Define linkage. Explain the effect of linkage on inheritance of two genes.


Question 18:

Explain transfer RNA (tRNA) as an adaptor molecule.


Question 19:

Comment upon the following: (i) Addiction (ii) Autoimmune disease.


Question 20:

What are lymphocytes? Comment upon two special types of lymphocytes present in our body.


Question 21:

What is cancer? Mention its prevention and cure.


Question 22:

What is sewage? Describe the biological treatment of sewage in short.


Question 23:

Comment upon the following: (i) Cloning (ii) Transgenic plants.


Question 24:

Describe the method of separation and isolation of fragments generated on cutting of DNA by restriction endonuclease.


Question 25:

Explain the application of biotechnology in agriculture.


Question 26:

Describe the different types of ecological pyramids in brief.


Question 27:

Define oogenesis. Describe the process of oogenesis with a diagram.


Question 28:

Write explanatory notes on the following: (i) Sterilization (ii) Infertility.


Question 29:

Describe the technique and application of DNA fingerprinting.


Question 30:

Write notes on the following: (i) Chromosomal aberrations (ii) Pedigree analysis.


Question 31:

Describe the different population interactions with suitable examples.


Question 32:

Comment upon the following: (i) Biodiversity hotspots (ii) Productivity.

UP Board Class 12 Biology 2026 Exam Pattern and Marking Scheme Explained

UPMSP set this paper (Set 348 EL) as 32 compulsory questions of rising difficulty, with the last three questions offering an internal choice.

  • Total questions: 4 one-mark MCQs, 5 one-mark short questions, 5 two-mark questions, 12 three-mark questions, and 3 five-mark questions with a choice (extracted as 6 rows)
  • Total marks: 70
  • Duration: 3 hours 15 minutes
  • Question types: objective (MCQ), short-answer and diagram-based descriptive answers
  • Internal choice: the final 3 questions (5 marks each, 15 marks total) each let you attempt one of two alternative questions
  • Diagrams: UPMSP instructs students to illustrate answers with labelled diagrams wherever necessary

High-Weightage Topics in UP Board Class 12 Biology 2026 to Focus On First

Based on this paper's actual question distribution across the first 26 questions (55 of the 70 marks, before the internal-choice questions), a few chapters clearly dominate.

  • Human Health and Disease: 11 of 55 marks - the single biggest chapter
  • Applications of Biotechnology: 9 of 55 marks
  • Ecosystem: 8 of 55 marks
  • Sexual Reproduction in Flowering Plants, and Molecular Basis of Inheritance: 7 of 55 marks each
  • Principles of Inheritance and Variation: 6 of 55 marks

The remaining 15 marks let you choose between long-answer questions across multiple chapters - practise as many as you can, since you only find out which alternative suits you better once you read the actual questions.

UP Board Class 12 Biology Question Paper Analysis Video

Source: ask board

How to Use the UP Board Biology Question Paper for Practice

Treat this Set 348 EL paper as a timed mock before you check the solutions.

  • Attempt all 32 questions in 3 hours 15 minutes under exam conditions first
  • For the final 3 choice questions, practise both alternatives, not just the one you'd normally pick
  • Draw and label the relevant diagram for every question that calls for one - UPMSP awards marks for correctly labelled diagrams separately from the written answer
  • Review each answer against the step-by-step solution PDF, not just the final answer

UP Board Class 12 Biology Student Reactions 2026

  • Reactions to this paper were mixed - some students found the human physiology and biotechnology questions familiar from NCERT practice, while others found the diagram-based questions time-consuming to complete neatly under time pressure

UP Board Class 12 Biology 2026 Question Paper FAQs

Ques. When was the UP Board Class 12 Biology 2026 exam conducted?

Ans. UPMSP conducted the UP Board Class 12 Biology 2026 exam on February 23, 2026, in the afternoon shift from 2:00 PM to 5:15 PM, as part of the intermediate exams that ran from February 18 to March 12, 2026.

Ques. How many questions are there in the UP Board Class 12 Biology 2026 paper, and is there any choice?

Ans. The paper has 32 questions worth 70 marks. The last 3 questions (5 marks each) each give you a choice between two alternative questions - you only need to attempt one from each pair.

Ques. What is the marking scheme for UP Board Class 12 Biology 2026?

Ans. The paper carries 70 marks in 3 hours 15 minutes: 4 one-mark MCQs, 5 one-mark short questions, 5 two-mark questions, 12 three-mark questions, and 3 five-mark questions with internal choice.

Ques. Which topics had the highest weightage in UP Board Class 12 Biology 2026 Set 348 EL?

Ans. Based on this paper's actual questions, Human Health and Disease (11 of the first 55 marks) led, followed by Applications of Biotechnology (9 marks) and Ecosystem (8 marks). The final 15 marks let you choose between long-answer questions across multiple chapters.

Ques. Where can I download the UP Board Class 12 Biology 2026 question paper with solutions PDF for free?

Ans. You can download both the question paper and the full step-by-step solutions PDF for Set 348 EL from the table at the top of this page, for free.