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Comorbidity is a medical condition or a disease that frequently co-exists with a primary medical condition or disease.
- Comorbidity can be physiological as well as psychological.
- It explains the impact of all other conditions a patient may have in addition to the primary disease.
- It is a term used frequently in the field of mental health to describe conditions that occur simultaneously with one another, such as depression and anxiety disorders.
- A person having comorbidity needs an extra level of health care as it decreases the person’s capability to function properly in day-to-day life.
- A person suffering from depression, diabetes, and high blood pressure is an example of Comorbidity.
| Table of Content |
Key Terms: Comorbidity, Multimorbidity, Immunity, Mental Health, Diabetes, Disorders, Coronavirus, Disease, COVID-19
What is Comorbidity?
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Comorbidity is a coexisting health condition along with any other primary disease or condition in a person. For instance, a heart attack often occurs with stroke or vascular disease. Another example would be chronic kidney disease that occurs with hypertension and anemia.
- Comorbidities are usually chronic in nature and may impact physical or mental health.
- A person can have many comorbidities at the same time.
- For example, a person may have anxiety, arthritis, and high blood pressure.
- Comorbidity is generally used when one particular condition is in the focus.
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Multimorbidity is the term used if more than two health conditions are present.

Comorbidity
History of Comorbidity
A.R. Feinstein, an American physician, and epidemiologist, coined the term ‘Comorbidity’ in the 1970s.
- Feinstein used the example of rheumatic fever patients who typically had a number of other ailments to define comorbid disorders.
- Since that time, comorbidity indicates having more than one medical or mental condition in the same person.
Read More:
| Relevant Concepts | ||
|---|---|---|
| Human Health and Diseases | Infectious Diseases | Deficiency Diseases |
| Chronic Disease and Poor Health | Principle of Treatment of Diseases | Human Diseases |
Types of Comorbidity
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The categorization of Comorbidity according to syndromal and nosological principles is primarily illustrative and inaccurate, but it enables us to comprehend that comorbidity may be related to a single cause or shared mechanisms of pathogens.
The various types of Comorbidity are as follows:
- Etiological Comorbidity
- Complicated Comorbidity
- Latrogenic Comorbidity
- Unknown Comorbidity
- Arbitrary Comorbidity
Causes of Comorbidity
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Some comorbidities can develop in people at random. People's seasonal allergies or arthritis are two examples of this. Non-random comorbidity can be caused by three main processes, including
One Disorder Causing Another
- In this cause of comorbidity, one illness directly contributes to the development of the other.
- For instance, continued drug or alcohol misuse can cause liver cirrhosis.
Effects of One Disorder Causing Another
- In this instance, the beginning of the second disorder is brought on by the side effects or indirect consequences of the first disorder.
- For instance, a patient with a cardiac condition may become stressed out and alter their lifestyle.
- Anxiety, which develops into the second disorder, may result from this.
Common Causes
- Common comorbidity triggers traumatic life events that might result in mood disorders, depression, or comorbid anxiety.
- When persons with frequently occurring mental disorders have severe comorbidities, biological and genetic factors can play a significant role.

Causes of Comorbidity
Treatment in Comorbidities
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It can be difficult for medical practitioners to make a precise primary diagnosis and plan the patient's course of treatment when there is an overlap of medical disorders. Additionally, it raises the patient's treatment costs.
To reduce the possibility of pharmaceutical issues like allergies or overdose on the same prescription, it is crucial that the doctor is informed of all medications that a patient is taking if they have more than one medical condition or disorder.
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| Related Topics | ||
|---|---|---|
| Acute and Chronic Diseases | Principles of Treatment | Virology |
| Human Bacterial Diseases | Modes of Transmission of Diseases | Viral Diseases |
Comorbidity and Coronavirus
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Doctors from all over the world have contributed their research on the relationship between comorbidity and its impact on COVID-19 infection in patients.
- The majority (48%) of coronavirus-related fatalities were caused by comorbid conditions.
- Out of these 48 percent, more than 30 percent had hypertension, 19 percent had diabetes, and about 8% had cardiovascular diseases.
- It may be generally stated that diabetes, hypertension, and cardiovascular disorders are some comorbidities that can speed up the rate at which the body is impacted by the coronavirus.
- Comorbidities have been shown to slow down a speedier recovery, as well.
Coronavirus is more likely to spread to those with compromised immune systems. Recent research indicates that people with comorbidities die more frequently than those without them.
- Hypertension: A coronavirus-affected patient's response to a full and quick recovery was hampered by hypertension as a comorbidity. It drastically lowers immunity, which makes it simpler for the infection to damage the person.
- Diabetes: The body's ability to fend against infections is significantly impacted by poor glycemic levels. Additionally, it triggers the development of bacterial infections in the lungs and abdomen.
- Cardiovascular Conditions: When the coronavirus strikes, patients with cardiovascular problems may suffer myocardial injury and cardiovascular collapse.
Things to Remember
- Comonrbidity is any co-existing medical condition existing with another primary disease or health condition.
- Comorbidities arise apart from one another and are not causally related.
- They may be linked by common genetic, behavioral, or environmental variables, whereas some comorbidities arise together at random.
- The cost of treatment is increased by comorbidity making it more difficult to treat a health problem.
- Comorbidities increase in frequency with growing age with adults being the most affected.
Sample Questions
Ques. Define Comorbidity. (3 Marks)
Ans. Comorbidity is defined as a medical condition or a disease that simultaneously exists in the body of a patient along with other medical conditions or diseases at the same time. The medical condition can be physical as well as mental. For instance, a person suffering from Coronavirus may be affected by diabetes and depression at the same time. The severity of the comorbidity affects a person’s responsiveness to the treatment of the principal diagnosis.
Ques. What are the causes of Comorbidity? (3 Marks)
Ans. There are three broad causes of Comorbidity:
- One Disorder Causing Another: A disorder directly causes the second disorder. For instance, alcohol abuse can lead to liver cirrhosis.
- Effects of One Disorder Causing Another: The side effects or indirect effects of one disorder cause the second disorder. For instance, a person suffering from a heart disorder may experience stress.
- Common Causes: Common traumatic life vents can lead to mood disorders, depression, or comorbid anxiety.
Ques. What distinguishes multimorbidity from comorbidity, and vice versa? (2 Marks)
Ans. Multimorbidity, as opposed to comorbidity, is the simultaneous presence of more than two diseases or illnesses in a single person. Comorbidity is the presence of more than one disease or sickness in a single person.
Ques. How are comorbidities eliminated? (3 Marks)
Ans. Treatment for particular comorbid conditions has shown potential in a number of ways.
- Therapy using cognitive behavior (CBT)
- Behavioral Dialectical Therapy (DBT)
- Advocacy in Community Treatment (ACT)
- Therapeutic Neighborhoods (TCs)
- Exposure therapy using contingency management (CM) or motivational incentives (MI).
Ques. Do comorbidities get worse as people age? (1 Mark)
Ans. Comorbidities are more common as people age. Over two-thirds of individuals over 65 have at least one comorbidity, and nearly a quarter have four or more.
Ques. How are comorbidities linked? (3 Marks)
Ans. Comorbidities can be linked due to various factors such as
- Chance occurrence between the two medical conditions.
- Due to overlapping risk factors.
- One condition is an outcome of the complications of the other.
- Both conditions are caused by a third condition.
Ques. What co-occurs most frequently with depression? (2 Marks)
Ans. Regardless of the severity of the depression, neurotic, stress-related, and somatoform disorders (F4) were by far the most common comorbidity. 65% of severe depression cases (52% of mild, and 61% of moderate cases) had also been diagnosed with F4.
Ques. What causes comorbidity to occur, and why? (3 Marks)
Ans. Comorbidity can happen for many different reasons. The comorbid condition may develop as a result of two disorders having shared or overlapping risk factors, as a result of one disorder causing the other, or as a result of chance or the confluence of independent risk factors. It may also be a multifaceted manifestation of one of the pure disorders or a third independent disorder.
As a result, the optimum strategy for managing comorbidity relies on the reasons why a specific pair of illnesses frequently co-occur.
Ques. Name some common Comorbidities. (3 Marks)
Ans. Some common comorbidities that frequently occur are as follows:
- Obesity
- Diabetes
- High Blood Pressure
- Heart Disease
- High Blood Lipid Levels
- Arthritis
- Asthma
- Sleep Apnea
- Osteoarthritis
- Depression
- Cancer
- Lung Disease
- Dementia
- Anxiety Disorders
Ques. What is the treatment in case of Comorbidity? (3 Marks)
Ans. In case of overlap of medical conditions, it is challenging for the health care professionals to do an accurate principal diagnosis and plan out the treatment course for the patient.
For instance, a person diagnosed with COVID-19 along with diabetes needs to be treated for both conditions. However, there may be an overlap between the symptoms and medications for both conditions., thus, there needs to be coordination between the various healthcare professionals providing treatment to the patient.
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