NCERT Solutions For Class 12 Biology Chapter 5: Principles of Inheritance and Variation

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NCERT Solutions for Class 12 Biology Chapter 5 Principles of Inheritance and Variation are provided in this article. It includes all the important definitions, concepts, and methodologies that will be beneficial for the students appearing for the CBSE Class 12 Exam 2024-25. Students can easily access the NCERT Solutions for class 12 by clicking on the download link below. The important topics that are included in this chapter are:

Expected no. of Questions: 3-4 questions of around 6 marks.

Download PDF: NCERT Solutions for Class 12 Biology Chapter 5 Principles of Inheritance and Variation


NCERT Solutions for Class 12 Biology Chapter 5

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Class 12 Biology Chapter 5 Principles of Inheritance and Variations: Important Topics

The Principle of Inheritance and Variation class 12 explains the study of heredity and variation principles along with their mechanism. Inheritance explains how characteristics are passed on from one generation to the next and that variation may depend on factors such as physical, mental, emotional, and behavioral. The important topics that are covered in this chapter are discussed below:

Mendelian Inheritance 

Mendelian inheritance is defined as certain patterns of how traits or characteristics are passed from parents to offspring. Austrian monk Gregor Mendel was the first person to establish these general patterns by performing thousands of experiments with pea plants in the 19th century.

The three laws of inheritance proposed by Mendel include: 

  • Law of Dominance: Law of Dominance, also known as Mendel’s first law of inheritance, according to which, hybrid offspring will only inherit the dominant trait in the phenotype.
  • Law of Segregation: According to the law of segregation during the production of gametes, two copies of each hereditary factor segregate so that offspring acquire one factor from each parent.
  • Law of Independent Assortment: Also known as Mendel’s second law of inheritance, this law states that a pair of traits segregate independently of another pair during gamete formation.

Read more: CBSE Class 12 Biology Chapter 5 notes

Chromosomal Theory of Inheritance

The chromosomal theory of inheritance, which was given by Boveri and Sutton in the early 1900s, is the fundamental theory of genetics.

  • This theory states that genes are the units of heredity and are found in the chromosomes. 
  • Experiments were performed on fruit flies and Drosophila Melanogaster. 

Sex Determination

The system used to determine whether an individual is a male or female is called sex determination.

  • Chromosomes used to identify the sex of the child are called sex chromosomes. 
  • When males produce two different gametes, it is called male heterogamety.
  • Female heterogamety means when a female produces two different gametes. 

Read more: Principle of Inheritance Important Questions

Genetic Disorders

The disorders which occur due to mutation in genes are called genetic disorders. The risk of such type of disorders is determined using pedigree charts or analysis. It is a study carried out to determine a disease by studying the inheritance pattern of the family. Mendelian and Chromosomal disorders are the two types of genetic disorders.

Mendelian Disorders

The disorders that affect one gene or result in mutations in the genome are called Mendelian disorders.

  • Colorblindness: Colourblindness is a disorder caused by mutation of genes present on the X chromosome. A person fails to see certain colours like red, blue, and green.
  • Hemophilia: In this disease, a protein responsible for clotting blood is affected. A person’s body fails to clot blood. 

Chromosomal Disorders

Any change in the chromosome of an individual is called a chromosomal disorder.

  • Down Syndrome is a condition wherein a person has an extra 21st chromosome.
  • Kleinfelters syndrome is a type of syndrome wherein a person has an extra X chromosome resulting in 47 chromosomes.
  • Turners syndrome results in the absence of an X chromosome ie; there are 45 chromosomes present in total.

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CBSE CLASS XII Related Questions

  • 1.
    Cow dung and water are mixed and fed into a biogas plant to allow digestion of biowastes. The person performing this process says that there is no need to provide an inoculum.
    Do you agree with him? Justify your answer.
    What happens to the biowaste inside the digester ?
    (c) Name the useful by-products obtained from this process and mention how they are used.


      • 2.
        Describe the experiment conducted by T.H. Morgan on Drosophila melanogaster involving eye colour and body colour.
        How did the results deviate from Mendelian inheritance pattern ?
        (c) Explain the two genetic terms used by Morgan for his observations.


          • 3.
            Oogenesis is a discontinuous process that begins before birth and is completed after puberty.
            Trace the development of a gamete mother cell till its release from the ovary during ovulation.
            Name the two pituitary hormones that play an important role in the process.


              • 4.
                Work out the crosses between:
                Normal female and Haemophilic male
                Carrier female and Normal male
                (III) Carrier female and Haemophilic male
                Write the conclusions you draw from these crosses. Comment on the type of inheritance of the disease.
                (Use: $X$ - Normal, $X^h$ - Haemophilic)


                  • 5.
                    In vitro fertilization (IVF) is a popular method these days that is helping childless couples to bear a child.
                    Write the different steps that are carried out in this technique.
                    Would you consider gamete intra fallopian transfer as a type of IVF? Justify your answer.


                      • 6.
                        What is meant by translation in protein synthesis?
                        Explain charging of tRNA (aminoacylation of tRNA) and mention its importance in the process of translation.

                          CBSE CLASS XII Previous Year Papers

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