Symptoms of Thyroid: Hypothyroidism & Hyperthyroidism

Symptoms of thyroid disorder includes many metabolic and physical changes in person. The thyroid gland, the butterfly-shaped gland, produces hormones that regulate the metabolic rate of the body, controlling the heart, muscle and digestive function. The thyroid disorder is caused due to malfunction of the thyroid gland.

  • Two type of thyroidism (thyroid disorder) can happen.
  • Hyper thyroidism occurs whern overactiveness of gland produce more than requird thyroid hormone.
  • Hypothyroidism is the condition where less hormone is produced by underactive thyroid gland.
  • Symptoms can be weight loss or gain, disturbed metabolism, irregualr menstruation in female etc.
  • Other thyroid disorder are goiter, hashimoto’s disease and grave’s disease.

key Terms: Thyroid, Thyroid gland, Hyperthyroidism, Hypothyroididm, Hormone, body, Disease.

Read more: Hypothalamus

What is thyroid Gland?

The thyroid gland is an endocrine gland that’s situated in the front of the neck, just below the Adam’s apple, covered around the trachea. It is formed like a butterfly with two wide wings that cover around the side of our throat. Human body has glands where  substances that support the body and do a major things are produced. Thyroid creates hormones that support and help control various vital functions of our body. 

  • If thyroid does not work perfectly and properly, it can affect the entire body.
  • If  body creates more and more thyroid hormones, It can develop a condition called hyperthyroidism.
  • Such situations are serious and essential to be treated by healthcare provider.​

Common Thyroid Disorders

The symptoms and signs of thyroidism differ, depending on the severity of the hormone deficiency. Problems tend to generate slowly, often over several years. The major thyroid abnormalities and diseases are as follows:

  • Hypothyroidism
  • Hyperthyroidism
  • Goitre
  • Hashimoto’s Disease
  • Grave’s Disease

What Is Hypothyroidism?

This medical condition results from low levels of circulating thyroid hormones. The greatest typical cause is first thyroid unwellness, often leading to myxedema, auto-immune in adults.

  • Women tend to become affected more than males.
  • In children, hypothyroidism causes physical and mental retardation. 
  • The thyroxine-binding globulin or TBG could also be higher, thanks to maternal hyperestrogenism.
  • The small feedback can elevate thyrotropic hormone level conjointly.
  • Treatment and prompt identification are essential for hypothyroidism since any delay at the beginning replacement might cause irreversible harm.
  • The maternal glandular condition may also cause baby hypothyroidism.
  • The secondary glandular issue may result from pituitary or hypothalamic reasons.
  • Estimation of thyrotropic hormone level and endocrine check can work to separate the different assortments of hypothalamic causes.
  • Hypothyroidism in adults causes myxoedema, portrayed by looseness under the eyes, enlarging of face, gradualness in physical and mental exercises.

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Symptoms of Hypothyroidism

Hypothyroidism develops various symptoms from which the condition is recognized. Few of them are listed below.

  • Increased sensitivity to cold
  • Weight gain
  • Constipation
  • Fatigue
  • Dry skin
  • Elevated blood cholesterol level
  • Muscle aches, tenderness and stiffness
  • Heavier than normal or irregular menstrual periods
  • Puffy face
  • Stiffness or swelling in your joints, Pain
  • Hoarseness
  • Slowed heart rate
  • Enlarged thyroid gland
  • Muscle weakness
  • Thinning hair
  • Impaired memory
  • Depression

Causes of Hypothyroidism

Less productio of thiroxine leads to several disorders.

Hashimoto’s Disease

It is the most common cause of hypothyroidism and is also called an autoimmune disorder or Hashimoto’s thyroiditis.

  • It takes place when the immune system produces antibodies and attack the body’s own tissues.
  • When these antibodies attack the thyroid gland, it makes the thyroid gland produce sufficient levels of hormones.
  • It may occur due to environmental factors, though the exact causes are still unknown. 

Response to Hyperthyroidism Treatment

At times, treatment of Hyperthyroidism may include the use of radioactive iodine or anti-thyroid medicines. This may lower the hormone levels, altering hyperthyroidism into hypothyroidism.

Surgery

Surgical removal of the thyroid gland either partly or completely may result into less production or no production of the hormone at all.

Radiation

The radiation therapy is given to the cancer patients which may affect the thyroid gland when parts of the neck and head undergo radiation resulting in hypothyroidism.

Medications: Some medicines out there also interfere with the activity of the thyroid like lithium. 

What is Hyperthyroidism? 

This condition is caused when thyroid organs unnecessarily produce a hormone called thyroxine. It is less common in comparison to hypothyroidism. Increased levels of thyroid hormone accelerate the body’s metabolism that leads to irregular weight loss, irregular heartbeat, etc.

Causes of Hyperthyroidism

Grave’s Disease: It is another autoimmune disease, wherein the immune system attacks the thyroid gland and thyroid gland produces so much thyroxine that it fails to fight back. Grave’s disease is hereditary which runs in the family.

Other causes of hyperthyroidism comprises swollen thyroid gland or outgrowths on the thyroid gland called thyroid nodules.

Goiter 

The term “goiter” is referred to as the abnormal enlargement of the thyroid gland. A goiter can occur in a gland which is producing too much hormone (hyperthyroidism) or too little hormone (hypothyroidism) or the correct amount of hormone (euthyroidism). 

Read More: Multinodular Goiter

Euthyroid Goiter

Iodine inadequacy may cause euthyroid goitre. There are raised thyrotropic hormone levels which may make proceeded with incitement of secretory organs bringing about dysplasia and goitre. Hormone levels are seen inside the lower furthest reaches of the normal value.

Goitrogenic Substances

These are the substances that meddle with the creation of thyroid hormones.These comprise thiocyanates, perchlorates and nitrates and the drugs such as thiourea, thiocarbamide, thiouracil, and so on. Certain plant food sources like cabbage and turnip contain goitrogenic factors.

Simple Endemic Goiter

This is because of iodine insufficiency in the eating regimen.

  • It is seen in the most part found in the geographical regions away from the ocean coast where the water and soil are low in iodine content.
  • The utilization of iodized salt is pushed to conquer the issue of endemic goitre.

Laboratory Diagnosis Of Thyroid Function

To diagnose the thyroid function, some laboratory based test can be done that checks the hormone level in body.

  • In order to check thyroid function, tests may include thyroid stimulating hormone (TSH), T4, T3, and thyroid antibody tests. 
  • Hypothyroidism is identified with limited PBI (Protein-bound iodine test) and hyperthyroidism with accumulated PBI.

Read More: Thyroid Stimulating Hormone

Thyroid cancer

It is a very simple form of cancer. Thyroid cancer can be of four types.

  • Medullary cancer
  • Papillary thyroid cancer
  • Anaplastic thyroid cancer
  • Follicular thyroid cancer

Things to Remember

  • The thyroid gland is situated in the front of the neck, just below the Adam’s apple.
  • The major thyroid abnormalities and diseases are as follows: Hypothyroidism, Hyperthyroidism, Goitre, Hashimoto’s Disease, Grave’s Disease.
  • All the problems that occurs due to thyroid malfunction causes metabolic imbalances.
  • Hypothyroidism is the condition which is caused by the under-secretion of thyroid hormones. 
  • It is an exceptionally normal issue and frequently remains undetected for quite a long time.
  • Hypothyroidism rises from the treatment of hyperthyroidism, antithyroid medicine or radioactive iodine.
  • Hyperthyroidism is the condition which is caused when thyroid organs unnecessarily produce a hormone called thyroxine. 
  • The symptoms can be a change for hunger, surprising weight reduction, a sleeping disorder, exhaustion, crabbiness, regular pee, expanded perspiring and warmth narrow mindedness.
  • A goiter can occur in a gland which is producing too much or too little hormone (hypothyroidism) or the correct amount of hormone (euthyroidism). 

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Sample Questions

Ques- What is Hashimoto’s Thyroiditis? (2 marks)

Ans- Hashimoto Thyroiditis is an autoimmune disease which means antibodies attacks the body’s tissues. Thus, when these antibodies attack the thyroid gland, it affects the thyroid glands capacity to produce sufficient levels of hormones.

Ques- What is Grave’s Disease? (2 marks)

Ans- It is an autoimmune disease wherein the thyroid gland is affected by immunity of body and in response the thyroid organ produces so much thyroxine that it can not fight back.

Ques- What are the symptoms of hyperthyrodism? (2 marks)

Ans- The symptoms of hyperthyrodism are as follows:

  • Feeling nervous, weak, tired, moody, etc.
  • Shaking of hand
  • Breathing problems
  • Faster heartbeat
  • Feeling hot, sweaty, warm
  • Red and itchy skin
  • Frequent bowel movements
  • Hair fall
  • Weight loss, more than usual appetite

Ques- What is meant by goitrogrnic substances? (1 marks)

Ans- Goitrogrnic are the substances that meddle with the creation of thyroid hormones. It consists thiocyanates, perchlorates and nitrates and the drugs such as thiourea, thiocarbamide, thiouracil.

Ques- What are the common disorders of hypothyroidism? (2 marks)

Ans-  The major thyroid diseases are as follows:

  • Hypothyroidism
  • Hyperthyroidism
  • Goitre
  • Hashimoto’s Disease
  • Grave’s Disease

Ques- What are the various diagnostic tests for hyperthyroid? (2 marks)

Ans- There are various diagnostic tests for hyperthyroid which are- Thyroid-stimulating immunoglobulin (TSI) test, thyroid scan, thyroid-stimulating hormone (TSH) test, radioactive iodine uptake test, T3 test and T4 test.

Ques- What do you mean by hyperthyroidism? Write its symptoms. (3 marks)

Ans- This condition is caused when thyroid organs produce more than enough thyroxine. It is less common in comparison to hypothyroidism. IBody’s metabolism gets overactive due to high level of hormone. It leads to irregular weight loss, irregular heartbeat, etc.

Its symptoms are:

  • Feeling nervous, weak, tired, moody, etc.
  • Shaking of hand
  • Breathing problems
  • Faster heartbeat
  • Feeling hot, sweaty, warm
  • Red and itchy skin

Ques. State the causes of hypothyroidism. (4 marks)

Ans.Hashimoto’s Disease: It is the most common cause of hypothyroidism. It takes place when the immune system produces antibodies and attack the tissues. So, when these antibodies attack the thyroid gland, it makes the thyroid gland produce sufficient levels of hormones. It may occur due to environmental factors.

Response to Hyperthyroidism Treatment: Treatment of Hyperthyroidism may include the use of radioactive iodine or anti-thyroid medicines. This may lower the hormone levels, altering hyperthyroidism into hypothyroidism.

Surgery: Surgical removal of the thyroid gland results into less production or no production of the hormone at all.

Radiation: The radiation therapy may affect the thyroid gland when parts of the neck and head undergo radiation. It causes hypothyroidism.

Ques- Differentiate between hypothyroidism and hyperthyroidism. (4 marks)

Ans- Hypothyroidism: This condition is caused by the under-secretion of thyroid hormones. It is an exceptionally normal issue and frequently remains undetected for quite a long time. One of the principal reasons that trigger hypothyroidism is an immune system problem called Hashimoto's infection. In this condition, the antibodies created by the body assault the thyroid organ and this outcome in the organs delivering fewer hormones.

Hyperthyroidism: This condition is caused when thyroid organs unnecessarily produce a hormone called thyroxine. The symptoms comprise a change for hunger, surprising weight reduction, a sleeping disorder, exhaustion, crabbiness, regular pee, expanded perspiring and warmth narrow mindedness. Be that as it may, this condition ordinarily settles inside a couple of long periods of significant medicines and proper medication.

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                          CBSE CLASS XII Previous Year Papers

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