Biomolecules: Types, Functions & Examples

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Arpita Srivastava

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Biomolecules are made up of chemical molecules which are fused together to form complex compounds. These are the compounds that are involved in the formation and metabolism of living organisms.

  • Biomolecules are used for the sustenance of life. 
  • Basically, every little thing in this universe is made up of tiny atoms.
  • Atoms are fused together via electrons to form compounds, which go on to form molecules.
  • It is also known as a biological molecule.
  • These molecules are produced within the organisms.
  • Nuclei acid is responsible for storing the genetic code of living organisms.
  • Oxygen, carbon, hydrogen, and nitrogen are structural elements of biomolecules.​
  • Carbon forms a covalent bond to form several other compounds.
  • Some biomolecules are derivatives of hydrocarbons.

Key Terms: Biomolecules, Carbohydrates, Amino Acids, Vitamins, Nucleic Acids, Proteins, Glucose, Fructose, Minerals, Water, Molecules, Nutrients, Monosaccharide, Oligosaccharides


What are Biomolecules?

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Biomolecules are an important element of living organisms and essential to many typical biological processes such as cell division and development. The main four kinds of biomolecules are carbohydrates, lipids, nucleic acids, and proteins.

  • Biomolecules perform an array of functions, including storing genetic information and serving as transporters.
  • These molecules serve as sources of stored energy and act as chemical messengers.
  • All biomolecules share a common structure and function.
  • They are the actual foot soldiers of the battle.
  • Biomolecules are referred to as biochemical universals.

Biomolecules

Biomolecules

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Types of Biomolecules

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Biomolecules include Carbohydrates, Proteins, Enzymes, Vitamins, Nucleic Acids, and Hormones. They are divided into two classes, which are as follows:

Inorganic Molecule

Molecules not bigger than 10-800 daltons in molecular weight are Inorganic Biomolecules. They are also known as micromolecules. For Example, Minerals, Water etc.

Organic Molecule

Molecules bigger than 800 Daltons in molecular weight are termed Organic Biomolecules. They are also known as Macromolecules. For example, Complex carbohydrates, Proteins, Nucleic acids, etc.

Carbohydrates

Carbohydrates are defined as polyhydroxy aldehydes or ketones compounds that produce biomolecule units on hydrolysis and are optically active. A few carbohydrates are also sweet in taste and are called sugars. These carbohydrates are classified based on their behaviour during hydrolysis.

  • Monosaccharides

Carbohydrates that cannot be hydrolyzed further into simpler, singular units are called monosaccharidesExamples are Glucose, Fructose, Ribose, etc.

  • Oligosaccharides

Carbohydrates that produce two to ten monosaccharide units on hydrolysis are called oligosaccharides. For Example, if one molecule of sucrose is hydrolyzed, it will give one molecule of glucose and one molecule of fructose.

  • Polysaccharides

Carbohydrates that produce more than ten monosaccharide units on hydrolysis are called polysaccharides. These are also known as non-sugars, as they do not taste sweet. Examples are Cellulose, starch, etc.

Different types of saccharides group are as follows:

Carbohydrates Formation Unit Functions

Sucrose

Glucose and Fructose

It’s a product of photosynthesis

Maltose Glucose and Glucose (alpha-1,4 linkage) Intermediate in starch and glycogen digestion

Lactose

Galactose and Glucose

A major animal energy source

Cellobiose

Glucose and Glucose (beta-1,4 linkage)

Essential in carbohydrate metabolism

Trehalose

Glucose and Glucose (alpha-1, alpha-1 linkage)

An energy source for insects

Gentiobiose

Glucose and Glucose (beta-1,6 linkage)

A constituent of plant glycosides and some polysaccharides

Types of Carbohydrates

Types of Carbohydrates

Amino Acids

Amino Acids are molecules that have one α-carbon at the centre and one amino (-NH₂), one Carboxyl (-COOH) and one Side chain (-R group). All these are functional groups.

  • It also consist of one hydrogen group on the four sides.

The amino acids are broadly divided into two classes based on their productivity in the human body:

  • Essential Amino Acid

The amino acids that cannot be synthesized by the organism and are very important for the overall growth and development of the organism are called Essential amino acids. Examples are valine, Leucine, etc.

  • Non-essential Amino Acids

The amino acids which can be synthesized by the human body are known as non-essential amino acids. Examples are Glycine, Alanine, etc.

Proteins 

Proteins, in all organisms, are made up of polypeptide chains or polymers of amino acids. These peptide chains are formed with the help of the peptide bonds.

  • These bonds are formed after a condensation reaction.
  • The reaction take place between -COOH group of one amino acid and the -NH2 group from one amino acid.
  • A polypeptide chain has more than a hundred amino acid residues.
  • It has a molecular mass of more than 10,000u.
  • Proteins are largely divided into two types, namely, Fibrous and Globular proteins.
  • The protein structure is broadly classified into Primary, Secondary, Tertiary, and Quaternary.

Nucleic Acids

The nucleosides are the chemical structures made up of a nitrogenous base and a ribose sugar unit. The chemical structures are made up of a nitrogenous base, a ribose sugar unit, and a phosphate sugar unit.

  • Nucleic acids are long polymer chains of nucleotides.
  • These nucleotides are joined together by the phosphodiester linkage between 5’ and 3’ C-atoms of a pentose sugar.
  • DNA double helix is derived from these nucleotides bonded together.
  • It is composed of two right-handed helical polynucleotide chains coiled spirally in an antiparallel direction.
  • Two strands of the DNA are held together by H-bonds.
  • Adenine forms a double bond with thymine.
  • Guanine forms a triple H-bond with cytosine.
  • The diameter of the double helix is 2nm, and one complete turn is 3.4 nm in length.

Total amount of A+G = Total amount of C+T

  • where A = Adenine
  • G = Guanine
  • T = Thymine
  • C= Cytosine

Vitamins

Vitamins are organic compounds required in the diet in very less amounts in order to take part in some important metabolic reactions. The deficiency of these vitamins could lead to long-term diseases in organisms, as listed below;

Vitamins Sources Deficiency disease
Vitamin A Fish liver oil, Carrots, Butter, and milk Xeropthalmia Night Blindness
Vitamin B₁ Yeast, Milk, green Vegetables, and cereals Beriberi
Vitamin B₂ Milk, egg white, liver, kidney Cheilosis
Vitamin B₆ Yeast, milk, egg yolk, cereals, and grams Convulsions
Vitamin B₁₂ Meat, fish, egg, and curd Pernicious anemia
Vitamin C Citrus fruits, amla, and green leafy vegetables Scurvy
Vitamin D Exposure to sunlight, fish, and egg yolk Rickets Osteomalacia
Vitamin E Vegetable oils like wheat germ oil, sunflower oil, etc. Increased fragility of RBCs and Muscular Weakness
Vitamin K Green Leafy Vegetables Increased Blood Clotting time

Functions of Biomolecules

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Biomolecules perform a variety of functions which are listed below:

  • Lipids form membranes and act as chemical messengers. 
  • Carbohydrates are essential energy resources forming structural components of living beings.
  • Proteins form antibodies and hormones and influence gene activities.
  • Nucleic acids, DNA, and RNA store genetic information. 

Important Topics for JEE Main

As per JEE Main 2024 Session 1, important topics included in the chapter Biomoleculesare as follows:

Subtopics Number of Questions Asked
Carbohydrates 1
Proteins 1
Amino Acids 1
Vitamins 1

Some memory based important questions asked in JEE Main 2024 Session 1 include:

  1. Among the given vitamins how many can be stored in the body (A, B1, B6, B12, C, D, E, & K).
  2. Hydrolysis of protein gives which type of amino acids? i. a - Amino acids ii. ẞ Amino acids iii. y Amino acids iv. 8 - Amino acids.
  3. Which structure of protein is intact after coagulation of egg white on boiling?
  4. Which of the given compounds will not give the Fehling test? i. Lactose ii. Maltose iii. Sucrose iv. Glucose

Things to Remember

  • Biomolecules are chemical molecules that are fused together to form complex compounds.
  • They include carbohydrates, proteins, enzymes, vitamins, nucleic acids, and hormones.
  • Nucleic acids are long polymer chains of nucleotides.
  • A few carbohydrates are also sweet in taste and are called sugars. 
  • Vitamin deficiencies could lead to long-term diseases in organisms such as scurvy, beriberi, rickets, etc.

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Sample Questions

Ques. Name some important commercial polymers? (2 marks)

Ans. The following are some important commercial Polymers:

  • Natural Rubber
  • Synthetic Rubbers
  • Buna Rubbers
  • General Purpose Styrene Rubber (GRS) or Buna-s
  • Teflon
  • Nylon-66
  • Nylon 6 or Perelon
  • Dacron
  • Phenol-formaldehyde polymer

Ques. Explain (A) Monosaccharides (B) Reducing Sugar? (2 marks)

Ans. (A) Monosaccharides: Monosaccharides are singular carbohydrate units that cannot be simplified further, on hydrolysis. These sugars are not decomposable and are usually classified as aldose or ketose, and they contain one or more hydroxyl groups per molecule. For example, Glucose and Fructose.

(B) Reducing Suhgar: Reducing sugar can be defined as sugars that act as reductants and can easily donate electrons to other molecules by oxidizing it is called reducing sugar. Eg; all monosaccharides are reducing in nature.

Ques. What is a peptide bond? (3 marks)

Ans. A peptide bond is a bond formed between two amino acid molecules as a result of a condensation reaction at the amino group of one amino acid and the carboxyl group of the other amino acid, producing a molecule of water. 

  • It forms amide type covalent bond.
  • Peptide bond links two alpha-amino acids to  one alpha-amino acid and N2 (nitrogen number two) of another.
  • The linkage is formed along a peptide chain.

Ques. Explain (A) Glycosidic Linkages (B) Denaturation of Proteins? (2 marks)

Ans. (A) Glycosidic Linkages: A glycosidic bond joins one sugar molecule to the other. These are formed between the hemiacetal or hemiketal group of a saccharide and the hydroxyl group of some compound such as alcohol.

(B) Denaturation of Proteins: The denaturation of proteins is a phenomenon that changes the structure of the protein due to the increasing temperature or pH. The secondary, tertiary, or quaternary structures are reduced to form a primary structure i.e. peptide chain.

Ques. What is glycogen? (3 marks)

Ans. Glycogen is a molecule that acts as a storage unit in mammals. The breakdown of these glycogen molecules creates glucose subunits, which are used for cellular respiration in an organism.

  • These glucose subunits help in the growth and development of the organism.
  • They are stored in the form of carbohydrates in human and mammals.
  • Each muscles in the skeletal contain 50,000 glucose moieties.
  • It is used as energy storage in animal, bacteria and fungi.

Ques. What are the products of sucrose and lactose on hydrolysis? (1 mark)

Ans. The Hydrolysis in disaccharides like sucrose and lactose gives the monosaccharides like glucose and fructose, and Glucose and Galactose, respectively.

Ques. What is the difference between fibrous and globular types of protein? (4 marks)

Ans. A distribution between fibrous and globular types of protein is given below:

Particulars Fibrous Globular
Shape Linear Roughly Spherical
Structure The polypeptide chains run parallel and are held together by hydrogen bonds or disulfide bonds. The polypeptide chains are coiled around each other to form a spherical structure, which is held together by the hydrogen and disulfide bonds.
Solubility in Water Insoluble Soluble
Examples Keratin, Collagen, etc. Insulin, Hemoglobin, etc.

Ques. What are (A) Disaccharides (B) Nitogenous Base? (2 marks)

Ans. (A) Disaccharides:Disaccharides are sugars that are formed due to the joining of two monosaccharides together via glycosidic linkages. Examples of disaccharides are Lactose, Sucrose, Maltose, etc.

(B) Nitogenous Base: Nitrogenous bases are molecules that contain nitrogen which has the chemical properties of a base. The nitrogenous bases are divided into Purines and Pyrimidines. These are Adenine (A), Guanine (G), Thymine (T) and Cytosine (C), and Uracil (U).

Ques. What is the difference between saturated and unsaturated fatty acid? (4 marks)

Ans. The difference between saturated and unsaturated fatty acid are as follows:

Saturated Fatty Acid Unsaturated Fatty Acid
Saturated fatty acid are those acid which contain single chain of carbon atoms. Unsaturated Fatty Acid are those acid which contain chain of carbon atoms with double bond.
It is solid at room temperature. It is liquid at room temperature.
Saturated fatty acid have high melting point. Unsaturated fatty acid have low melting point.
They are long lasting and do not get spoiled easily. They do get spoiled easily.

Ques. What are the chemical constituents used in DNA and RNA? (4 marks)

Ans. The chemical constituents used in DNA are as follows:

  • Sugar: In case of sugar, DNA contains different form of deoxyribose which is a five-carbon sugar.
  • Bases: In case of bases, DNA is made of four nitrogenous bases namely adenine (A), thymine (T), cytosine (C), and guanine (G).
  • Phosphate: In this DNA molecule is made of phosphate group.

The chemical constituents used in RNA are as follows:

  • Sugar: In case of sugar, RNA contains different form of ribose which is a five-carbon sugar.
  • Bases: In case of bases, RNA is made of four bases namely includes adenine (A), uracil (U), cytosine (C), and guanine (G).
  • Phosphate: In this RNA molecule is made of phosphate group.

Ques. Explain different types of amino acid based on the charge? (3 marks)

Ans. The different types of amino acid are as follows:

  • Acidic Amino Acid: Amino acid that consists of negative charge on the compound are called acidic amino acid. For example: Glutamic acid
  • Basic Amino Acid: Amino acid that consists of positive charge on the compound are called acidic amino acid. For example: Lysine
  • Neutral Amino Acid: Amino acid that consists of no charge on the compound are called acidic amino acid. For example: Glycine and Alanine

Ques. In how many categories proteins are divided on the basis of structure? (4 marks)

Ans. Proteins are divided into four categories on the basis of structure which are as follows:

  • Primary Structure: This is the first structure of protein where the number of polypeptides compounds are involved in the sequence of amino acids.
  • Secondary Structure: This is the secondary structure of protein which form helix like structure. α helix, β pleated and collagen are three types of secondary structure.
  • Tertiary Structure: This is the tertiary structure of protein which form a hollow woollen ball to give a three dimensional view of protein.
  • Quaternary Structure: This is the fourth structure of protein which act as a subunit of protein.

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